The Gentell DuraGen® DP5022Plus Dural Regeneration Matrix is a biocompatible onlay dural graft designed for the repair and regeneration of dura mater.
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Key Features:
- Enhanced Porosity and Strength: Improved porosity and strength for optimal handling and integration.
- Ultra Pure Collagen™: Made from a controlled collagen source treated to remove antigenic components, minimizing rejection risk.
- Rapid Fibrin Clot Formation: Porous collagen scaffold promotes rapid fibrin clot formation for a watertight seal, preventing CSF leakage.
- Promotes Natural Dural Growth: Provides a scaffold for fibroblast migration and new collagen deposition, facilitating dural regeneration.
- Excellent Conformability and Adherence: Hydrates to conform to complex tissue surfaces.
- Scientifically Proven: Supported by numerous published clinical studies demonstrating safety and efficacy.
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Mechanism of Action:
- Rapid fibrin clot formation creates a watertight barrier.
- Fibroblasts migrate into the matrix and deposit new collagen.
- A neodural membrane forms within two weeks.
- The implant is resorbed and replaced by dura within 6-8 weeks.
- Mature dura develops after one year.
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Clinical Data Highlights: (Based on published studies)
- Low infection rate (1.9%)
- Low leakage rate (2.1%)
- 0% foreign body response reported.
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Applications:
- Dural repair and regeneration.
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Specifications:
- Size: 2″ x 2″ (5cm x 5cm)
- Quantity: 5 units per package
- Material: Ultra Pure Collagen™ matrix
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